Tag Archives: ISCI

Study finds combination stem cell therapy improves cardiac function

A new study from the Interdisciplinary Stem Cell Institute (ISCI) at the University of Miami Miller School of Medicine finds that combination stem cell therapy, using c-kit+ cardiac stem cells (CSCs) and mesenchymal stem cells (MSCs) can significantly enhance cardiac performance in chronic ischemic cardiomyopathy following a heart attack. This is the first time a combination of cells has been used in a large animal pre-clinical trial of established heart failure by researchers at ISCI.

Dr. Joshua Hare, director of Interdisciplinary Stem Cell Institute, led the study, Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy, which was published November 2, 2015 in the Journal of the American College of Cardiology.

“Previous work from our laboratory strongly supported the scientific rationale for cell combination therapy,” says Hare. “Now, as the field is growing, ISCI is showing the benefit of combining multiple types of cells to produce a stronger, more effective treatment option for patients with severe heart damage and heart failure.”