Tag Archives: UCLA

Stem cell gene therapy developed at UCLA holds promise for eliminating HIV infection

Method modifies immune cells to attack the virus, could be used to treat other diseases

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are one step closer to engineering a tool that could one day arm the body’s immune system to fight HIV — and win. The new technique harnesses the regenerative capacity of stem cells to generate an immune response to the virus.

The findings were published today in the journal Molecular Therapy.

HIV/AIDS: Progress and Promise in Stem Cell Research

CIRM has funded two HIV/AIDS Disease Teams led by scientists at UCLA and the City of Hope who are focused on stem cell transplant strategies that promise a long lasting resistance to HIV. Antiretroviral therapy provides life-saving medicine to HIV-infected people but it is not a cure. Long-term exposure to the drugs and the virus itself shorten a person’s life, even if they don’t develop AIDS. Both disease teams have a goal of getting to clinical trials within four years. For more info, go to: www.cirm.ca.gov/HIV/AIDS_facts