Stem cell research paves way for progress on dealing with Fragile XTue, 22 May 2012 08:45:45 EDTResearchers have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. The discovery paves the way for research that will examine restoration of normal gene expression in Fragile X patients.
Physical properties predict stem cell outcomeMon, 21 May 2012 16:37:37 EDTTissue engineers can use mesenchymal stem cells derived from fat to make cartilage, bone, or more fat. The best cells to use are ones that are already likely to become the desired tissue. Researchers have discovered that the mechanical properties of the stem cells can foretell what they will become, leading to a potential method of concentrating them for use in healing.
Growth factor in stem cells may spur recovery from multiple sclerosisMon, 21 May 2012 10:46:46 EDTA substance in human mesenchymal stem cells that promotes growth appears to spur restoration of nerves and their function in rodent models of multiple sclerosis, researchers have found.
Multipotent stromal stem cells from normally discarded human placental tissue demonstrate high therapeutic potentialFri, 18 May 2012 13:22:22 EDTPlacental stem cells with important therapeutic properties can be harvested in large quantities from the fetal side of human term placentas (called the chorion). The chorion is a part of the afterbirth and is normally discarded after delivery, but it contains stem cells of fetal origin that appear to be pluripotent -- i.e., they can differentiate into different types of human cells, such as lung, liver, or brain cells. Since these functional placental stem cells can be isolated from either fresh or frozen term human placentas, this implies that if each individual’s placenta is stored at birth instead of thrown away, these cells can be harvested in the future if therapeutic need arises. This potential represents a major breakthrough in the stem cell field.
New technique reveals unseen information in DNA codeThu, 17 May 2012 13:20:20 EDTScientists have used a new technique to map 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in DNA from human and mouse embryonic stem cells, revealing new information about their patterns of distribution. These studies have revealed that these DNA modifications play major roles in fundamental life processes such as cell differentiation, cancer and brain function.